EMD-73755

Single-particle
3.0 Å
EMD-73755 Deposition: 04/11/2025
Map released: 17/06/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73755

Cryo-EM structure of human TRPM4 channel in the warm conformation in complex with calcium and TPPO at 37 degrees Celsius (monomeric TMD-focused map with best-resolved TPPO density)

EMD-73755

Single-particle
3.0 Å
EMD-73755 Deposition: 04/11/2025
Map released: 17/06/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human TRPM4 channel in the warm conformation in complex with calcium and TPPO at 37 degrees Celsius
Fitted models: 9z1x

Deposition Authors: Jinhong H, Wei L, Juan D
Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology
DOI: doi:10.1038/s41594-026-01818-3
ISSN: 1545-9985