EMD-73657

Single-particle
3.3 Å
EMD-73657
3D View Gallery
Deposition: 29/10/2025
Map released: 13/05/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73657

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9yyv summary report (pdf.gz) Map-9yyv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)

EMD-73657

Single-particle
3.3 Å
EMD-73657
3D View Gallery
Deposition: 29/10/2025
Map released: 13/05/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: VN01H1 Fab-bound SARS-CoV-2 E-FIC
Fitted models: 9yyv

Deposition Authors: Park YJ , Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M , Case JB , Brown JT, Park YJ , Lee J, Sutherland E , Aggarwal A, Gibson C, Lempp FA , Stewart C , Tortorici MA , Sanapala S, Low JS, Asarnow D , Bohan D , Dellota Jr E, Merz B, Chawla B, Kar S, Lanzavecchia A , Sallusto F, Riley NM , Turville S, Purcell L, Diamond MS , Veesler D
(2026) Nat Struct Mol Biol , 33 , 810 - 823
PUBMED: 42050172
DOI: doi:10.1038/s41594-026-01801-y
ISSN: 1545-9985