EMD-73392
Cryo-EM structure of SARS-CoV-2 Omicron neutralizing antibody AB2-122 with BA.5 RBD and SP1-77 Fab complex
EMD-73392
Single-particle3.0 Å
Deposition: 18/10/2025Map released: 29/07/2026
Last modified: 29/07/2026
Sample Organism:
Mus musculus,
Severe acute respiratory syndrome coronavirus
Sample: AB2-122 with BA.5 RBD and SP1-77 Fab complex
Fitted models: 9ysg
Deposition Authors: Jonaid G, Batra H, Kibria G, Chen B
,
Alt FW
Sample: AB2-122 with BA.5 RBD and SP1-77 Fab complex
Fitted models: 9ysg
Deposition Authors: Jonaid G, Batra H, Kibria G, Chen B
,
Alt FW
Recurrent SARS-CoV-2 Omicron broadly neutralizing humanized antibodies in different single human V H 1-2-rearranging mouse models.
Batra H,
Luo S,
Saunders KO,
Higgins JS,
Jian F ,
Zhang J ,
Kibria MG ,
Jonaid GM,
Zhou QJ,
Eaton A,
Cronin K,
Mallory ML,
Mattocks M ,
Edwards RJ,
Parks R,
Lee EM,
Ye AY,
Williams AC ,
Jung G,
Mansouri K,
Alam SM,
Montefiori DC,
Tian M,
Baric RS ,
Cao Y ,
Haynes BF,
Chen B ,
Alt FW
(2026) PNAS , 123 , e2537053123 - e2537053123
,
Zhang J ,
Kibria MG ,
Jonaid GM,
Zhou QJ,
Eaton A,
Cronin K,
Mallory ML,
Mattocks M ,
Edwards RJ,
Parks R,
Lee EM,
Ye AY,
Williams AC ,
Jung G,
Mansouri K,
Alam SM,
Montefiori DC,
Tian M,
Baric RS ,
Cao Y ,
Haynes BF,
Chen B ,
Alt FW
(2026) PNAS , 123 , e2537053123 - e2537053123
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)
- Massachusetts Consortium on Pathogen Readiness (MassCPR): (United States)