EMD-73229

Single-particle
5.3 Å
EMD-73229
3D View Gallery
Deposition: 12/10/2025
Map released: 13/05/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73229

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focused map of HBV Capsid with compound HAP12

EMD-73229

Single-particle
5.3 Å
EMD-73229
3D View Gallery
Deposition: 12/10/2025
Map released: 13/05/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Hepatitis B virus subtype adyw, Homo sapiens
Sample: Hepatitis B virus subtype adyw

Deposition Authors: Gibes NG , Wang JC-Y , Zlotnick A , Kumar S
Negative cooperativity drives activity of capsid-directed antivirals against hepatitis B virus.
Valkner CJ, Gibes N, Xie MS, Nair S, Kumar S , Francis S, Venkatakrishnan B, Tsvetkova I, Patterson A, VanNieuwenhze M, Dragnea B, Wang JC, Zlotnick A
(2026) Sci Adv , 12 , eaed6483 - eaed6483
PUBMED: 42284399
DOI: doi:10.1126/sciadv.aed6483
ISSN: 2375-2548