EMD-73227
Focused map of HBV with BAY41-4109
EMD-73227
Single-particle7.9 Å
Deposition: 12/10/2025Map released: 13/05/2026
Last modified: 24/06/2026
Sample Organism:
Hepatitis B virus subtype adyw,
Hepatitis B virus
Sample: Hepatitis B virus subtype adyw
Deposition Authors: Gibes NG
,
Wang JC-Y ,
Zlotnick A ,
Kumar S
Sample: Hepatitis B virus subtype adyw
Deposition Authors: Gibes NG
,
Wang JC-Y ,
Zlotnick A ,
Kumar S
Negative cooperativity drives activity of capsid-directed antivirals against hepatitis B virus.
Valkner CJ,
Gibes N,
Xie MS,
Nair S,
Kumar S ,
Francis S,
Venkatakrishnan B,
Tsvetkova I,
Patterson A,
VanNieuwenhze M,
Dragnea B,
Wang JC,
Zlotnick A
(2026) Sci Adv , 12 , eaed6483 - eaed6483
,
Francis S,
Venkatakrishnan B,
Tsvetkova I,
Patterson A,
VanNieuwenhze M,
Dragnea B,
Wang JC,
Zlotnick A
(2026) Sci Adv , 12 , eaed6483 - eaed6483
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI118933 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI144022 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI173104 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI043453 (United States)