EMD-73220

Single-particle
3.06 Å
EMD-73220
3D View Gallery
Deposition: 11/10/2025
Map released: 08/04/2026
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73220

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ynp summary report (pdf.gz) Map-9ynp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Escherichia coli transcription initiation complex with GpA and pseudouridimycin (PUM)

EMD-73220

Single-particle
3.06 Å
EMD-73220
3D View Gallery
Deposition: 11/10/2025
Map released: 08/04/2026
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli str. K-12 substr. MG1655
Sample: Escherichia coli transcription initiation complex with GpA and pseudouridimycin (PUM)
Fitted models: 9ynp

Deposition Authors: You LL, Ebright RH
Solid-phase synthesis and biological evaluation of des-hydroxy pseudouridimycin analogs.
Anwar AF, You L, Degen D, Burns KJ, Garza MJ, Ebright RH, Del Valle JR
(2026) Acs Med.Chem.Lett. , 17 , 835 - 840
PUBMED: 41890570
DOI: doi:10.1021/acsmedchemlett.5c00684
ISSN: 1948-5875