EMD-7310

Single-particle
10.1 Å
EMD-7310
3D View Gallery
Deposition: 20/12/2017
Map released: 31/01/2018
Last modified: 03/02/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-7310
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Structure of human PRC2 bound to a hetero-dinucleosome substrate with 35 bp linker DNA. 3D classification of signal subtracted particles lacking the unmodified substrate nucleosome. Example Class3.

EMD-7310

Single-particle
10.1 Å
EMD-7310
3D View Gallery
Deposition: 20/12/2017
Map released: 31/01/2018
Last modified: 03/02/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human Polycomb Repressive Complex 2 (PRC2) in complex with a heterodinucleosome composed of an unmodified nucleosome and a nucleosome carrying an H3K27 pseudo-trimethyl mark with 35 bp. Subclassification of the overall reconstruction after signal subtraction. Example Class3.

Deposition Authors: Poepsel S, Kasinath V, Nogales E
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes.
Poepsel S , Kasinath V, Nogales E
(2018) Nat. Struct. Mol. Biol. , 25 , 154 - 162
PUBMED: 29379173
DOI: doi:10.1038/s41594-018-0023-y
ISSN: 1545-9985