EMD-72733

Single-particle
4.5 Å
EMD-72733
3D View Gallery
Deposition: 16/09/2025
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72733
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9yap summary report (pdf.gz) Map and 9yap FULL report (pdf.gz)
EMICSS annotations (xml)

Gbg crosslinked to PLCb3 - second conformation

EMD-72733

Single-particle
4.5 Å
EMD-72733
3D View Gallery
Deposition: 16/09/2025
Map released: 18/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus
Sample: BMPEG-crosslinked complex of Gb1g2 and PLCb3
Fitted models: 9yap

Deposition Authors: Fisher IJ, Lyon AM
G beta gamma engages PLC beta 3 at multiple sites to reorient and facilitate its activation.
Fisher IJ, Senarath K, Outlaw K, Muralidharan K, Garland-Kuntz EE, Van Camp M, Komay T, Inoue A, Kostenis E , Lambert NA , Lyon AM
(2026) bioRxiv
PUBMED: 41648476
DOI: doi:10.64898/2026.01.14.699417
ISSN: 2692-8205