EMD-72728

Helical reconstruction
3.12 Å
EMD-72728
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Deposition: 16/09/2025
Map released: 22/04/2026
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72728
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9yai summary report (pdf.gz) Map and 9yai FULL report (pdf.gz)
EMICSS annotations (xml)

KIF1A R350W bound to microtubules in two-heads-bound state with AMP-PNP

EMD-72728

Helical reconstruction
3.12 Å
EMD-72728
3D View Gallery
Deposition: 16/09/2025
Map released: 22/04/2026
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa, Homo sapiens
Sample: KIF1A R350W bound to microtubules in two-heads-bound state with AMP-PNP
Fitted models: 9yai

Deposition Authors: Shatarupa A, Rao L, Asenjo AB, Gennerich A, Sosa H
Pathogenic KIF1A R350 mutations disrupt a conserved and conformation-dependent kinesin-tubulin salt bridge.
Shatarupa A, Rao L, Asenjo AB, Gennerich A, Sosa H
(2026) Nat Commun
PUBMED: 41912506
DOI: doi:10.1038/s41467-026-71026-6
ISSN: 2041-1723