EMD-72653

Single-particle
3.26 Å
EMD-72653
3D View Gallery
Deposition: 09/09/2025
Map released: 15/10/2025
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72653
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9y7d summary report (pdf.gz) Map and 9y7d FULL report (pdf.gz)
EMICSS annotations (xml)

Cereblon with Golcadomide and Ikaros ZF1-2-3

EMD-72653

Single-particle
3.26 Å
EMD-72653
3D View Gallery
Deposition: 09/09/2025
Map released: 15/10/2025
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cereblon with Golcadomide with Ikaros ZF1-2-3
Fitted models: 9y7d

Deposition Authors: Watson ER, Lander GC
Golcadomide: An Oral CELMoD Agent Targeting IKZF1/3 for Diffuse Large B-cell Lymphoma.
Mo Z, Groocock L, Wood S, Jankeel D, Mendy D, Watson ER, Kai Y, Deb G, Cote M, Janardhanan P, Fernandez-Deudero A, Barnes L, Peng S, Groza M, Kalashnikova E, Angelo M, Zhu J, Galasso R, Jang IS, Castillo MS, Fontanillo C, Polido G, Christoforou A, Kercher T, Lander GC, Wang K, Narla RK, Carrancio S, Pierce DW, Rolfe M, Bence N, Lopez-Girona A
(2026) Blood Cancer Discov , 7 , 104 - 128
PUBMED: 41182271
DOI: doi:10.1158/2643-3230.BCD-25-0059
ISSN: 2643-3249
Grant Support: