EMD-72285

Single-particle
3.39 Å
EMD-72285
3D View Gallery
Deposition: 22/08/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72285

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM map of human MDA5 T331I mutant filament formed on short dsRNA

EMD-72285

Single-particle
3.39 Å
EMD-72285
3D View Gallery
Deposition: 22/08/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of human MDA5 T331I mutant with dsRNA

Deposition Authors: Xu L , Chung K , Pyle A

Unraveling the molecular basis for MDA5 T331I disease-linked mutation
Xu L , Chung K , Guo R, Pan A, Pyle AM
To Be Published
Grant Support: