EMD-72215
Focused cryo-EM map of DDB1dB:CRBN:mezigdomide:SALL4(392-449; G416A)
EMD-72215
Single-particle2.93 Å
Deposition: 19/08/2025Map released: 03/09/2025
Last modified: 03/09/2025
Sample Organism:
Homo sapiens
Sample: Ternary complex of DDB1dB:CRBN:mezigdomide:SALL4(392-449;G416A)
Deposition Authors: Park J
,
Hunkeler M ,
Roy Burman SS ,
Fischer ES
Sample: Ternary complex of DDB1dB:CRBN:mezigdomide:SALL4(392-449;G416A)
Deposition Authors: Park J
,
Hunkeler M ,
Roy Burman SS ,
Fischer ES
Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation.
Slabicki M,
Park J ,
Nowak RP,
Roy Burman SS ,
Pellman J,
Zou C,
Razumkov H,
Carreiro J,
Rastogi S,
Goldstein A,
Nagiec MM,
Donovan KA,
Che J,
Hunkeler M ,
Geng Q,
Hsu CL,
Lakshminarayan M,
Shu C,
Zon RL,
Kozicka Z ,
Park PMC,
Tsai JM,
Yoon H,
Jones LH,
Sperling AS,
Gray NS ,
Fischer ES ,
Ebert BL
(2025) Mol Cell , 85 , 3184 - 3201.e14
,
Nowak RP,
Roy Burman SS ,
Pellman J,
Zou C,
Razumkov H,
Carreiro J,
Rastogi S,
Goldstein A,
Nagiec MM,
Donovan KA,
Che J,
Hunkeler M ,
Geng Q,
Hsu CL,
Lakshminarayan M,
Shu C,
Zon RL,
Kozicka Z ,
Park PMC,
Tsai JM,
Yoon H,
Jones LH,
Sperling AS,
Gray NS ,
Fischer ES ,
Ebert BL
(2025) Mol Cell , 85 , 3184 - 3201.e14
Grant Support: