EMD-72202

Single-particle
2.5 Å
EMD-72202
3D View Gallery
Deposition: 18/08/2025
Map released: 19/08/2026
Last modified: 02/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72202

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9q3l summary report (pdf.gz) Map-9q3l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of beta2-adrenergic receptor dimer mediated by a biased allosteric modulator in lipid nanodisc

EMD-72202

Single-particle
2.5 Å
EMD-72202
3D View Gallery
Deposition: 18/08/2025
Map released: 19/08/2026
Last modified: 02/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dimeric beta2-adrenergic receptor bound to a biased allosteric modulator in nanodisc
Fitted models: 9q3l

Deposition Authors: Shen J , Kobilka BK
A biased allosteric modulator is a molecular glue for beta 2 AR dimerization.
Shen J , Peddada TN , Komolov KE , De Pascali F, Garces AM, Wang H, Ehsan M , Chae PS, Lerch MT , Benovic JL, Xu J , Kobilka BK
(2026) Nature
PUBMED: 42618785
DOI: doi:10.1038/s41586-026-10892-y
ISSN: 1476-4687
ASTM: NATUAS