EMD-72136
NediV IRES (A site) in complex with Rabbit 80S ribosome
EMD-72136
Single-particle3.5 Å
Deposition: 14/08/2025Map released: 17/06/2026
Last modified: 17/06/2026
Sample Organism:
Oryctolagus cuniculus,
Nedicistrovirus TFN-2012
Sample: Rabbit 80S ribosome with NediV IRES
Fitted models: 9q1q
Deposition Authors: De S
,
Altomare CG,
Abaeva IS,
Dadhwal P,
Garg P,
Acosta-Reyes F,
Brown ZP,
Pestova TV ,
Hellen CUT ,
Frank J
Sample: Rabbit 80S ribosome with NediV IRES
Fitted models: 9q1q
Deposition Authors: De S
,
Altomare CG,
Abaeva IS,
Dadhwal P,
Garg P,
Acosta-Reyes F,
Brown ZP,
Pestova TV ,
Hellen CUT ,
Frank J
Structural studies of nedicistrovirus IRES-driven, initiation factor-independent translation shed light on key steps of eukaryotic translation elongation.
De S ,
Altomare CG,
Abaeva IS,
Dadhwal P,
Garg P,
Acosta-Reyes F,
Brown ZP,
Pestova TV ,
Hellen CUT ,
Frank J
(2026) Nucleic Acids Res , 54
,
Altomare CG,
Abaeva IS,
Dadhwal P,
Garg P,
Acosta-Reyes F,
Brown ZP,
Pestova TV ,
Hellen CUT ,
Frank J
(2026) Nucleic Acids Res , 54
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35 GM139453 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35 GM122602 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM097014 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R21 AI188505 (United States)