EMD-72127

Single-particle
2.81 Å
EMD-72127
3D View Gallery
Deposition: 14/08/2025
Map released: 24/09/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72127

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9q1j summary report (pdf.gz) Map-9q1j FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 E191A mutant-T20P14-R complex

EMD-72127

Single-particle
2.81 Å
EMD-72127
3D View Gallery
Deposition: 14/08/2025
Map released: 24/09/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Complex of SARS-CoV-2 nsp10-nsp14 E191A mutant with a synthetic T20P14-R and P7 RNA
Fitted models: 9q1j

Deposition Authors: Yang Y , Liu C , Liu B
Molecular basis of SARS-CoV-2 proofreading enzyme-mediated resistance to remdesivir.
Yang Y , Li Y, Becker ST, Khan A, Luo G, Liu B , Liu C
(2025) PNAS , 122 , e2519755122 - e2519755122
PUBMED: 41032524
DOI: doi:10.1073/pnas.2519755122
ISSN: 1091-6490
ASTM: PNASA6