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EMD-72127

Single-particle
2.81 Å
EMD-72127
3D View Gallery
Deposition: 14/08/2025
Map released: 24/09/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72127
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9q1j summary report (pdf.gz) Map and 9q1j FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 E191A mutant-T20P14-R complex

EMD-72127

Single-particle
2.81 Å
EMD-72127
3D View Gallery
Deposition: 14/08/2025
Map released: 24/09/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Complex of SARS-CoV-2 nsp10-nsp14 E191A mutant with a synthetic T20P14-R and P7 RNA
Fitted models: 9q1j

Deposition Authors: Yang Y, Liu C, Liu B
Molecular basis of SARS-CoV-2 proofreading enzyme-mediated resistance to remdesivir.
Yang Y, Li Y, Becker ST, Khan A, Luo G, Liu B, Liu C
(2025) PNAS , 122 , e2519755122 - e2519755122
PUBMED: 41032524
DOI: doi:10.1073/pnas.2519755122
ISSN: 1091-6490
ASTM: PNASA6