EMD-72120

Single-particle
3.4 Å
EMD-72120 Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72120

Class III (T1D0) of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG

EMD-72120

Single-particle
3.4 Å
EMD-72120 Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Class III (T1D0) of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG
Fitted models: 9q19

Deposition Authors: Wang Y, Liu B, He Y, Feigon J
Structures of human telomerase with BIBR1532 reveal novel mechanism of inhibition.
Wang Y, Liu B, He Y, Feigon J
(2026) Nat Chem Biol
PUBMED: 42230822
DOI: doi:10.1038/s41589-026-02238-6
ISSN: 1552-4469