EMD-72118

Single-particle
3.3 Å
EMD-72118 Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72118

Class I (T1D0+) of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG

EMD-72118

Single-particle
3.3 Å
EMD-72118 Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Class I (T1D0+) of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG
Fitted models: 9q17

Deposition Authors: Wang Y, Liu B, He Y, Feigon J
Structures of human telomerase with BIBR1532 reveal novel mechanism of inhibition.
Wang Y, Liu B, He Y, Feigon J
(2026) Nat Chem Biol
PUBMED: 42230822
DOI: doi:10.1038/s41589-026-02238-6
ISSN: 1552-4469