EMD-72100

Single-particle
2.8 Å
EMD-72100
3D View Gallery
Deposition: 13/08/2025
Map released: 03/06/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72100

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9q0n summary report (pdf.gz) Map-9q0n FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of PPAT-NUDT5 complex bound to 6-methylthioinosine-5'-monophosphate (6-meTIMP)

EMD-72100

Single-particle
2.8 Å
EMD-72100
3D View Gallery
Deposition: 13/08/2025
Map released: 03/06/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of PPAT and NUDT5 with 6-methylthioinosine-5'-monophosphate
Fitted models: 9q0n

Deposition Authors: Witus SRW, Yang Z, Rape M

Regulation of purine synthesis and chemotherapy response by metabolite-derived molecular glues
Witus SRW, Kober MM, Roh H, Yang Z, Choueiry F, Ghate A, Titov DV, Rape M
To Be Published