EMD-72019

Single-particle
8.68 Å
EMD-72019
3D View Gallery
Deposition: 07/08/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72019
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Engaged-state naloxone-mu opioid receptor-Gi GDP complex (constant GDP) - Locally refined map

EMD-72019

Single-particle
8.68 Å
EMD-72019
3D View Gallery
Deposition: 07/08/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Naloxone-mu opioid receptor in complex in complex with Gai-GDP, Gb1 and Gg2

Deposition Authors: Gati C, Khan S, Han GW

Ligand efficacy is driven by conformational control of nucleotide exchange at the mu opioid receptor.
Khan S, Han GW, Gati C
To Be Published