EMD-71880

Single-particle
2.52 Å
EMD-71880
3D View Gallery
Deposition: 31/07/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71880

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pv0 summary report (pdf.gz) Map-9pv0 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

NorA in outward-open conformation bound to inhibitor IMP2380

EMD-71880

Single-particle
2.52 Å
EMD-71880
3D View Gallery
Deposition: 31/07/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Staphylococcus aureus, Escherichia coli
Sample: NorA-BRIL in complex with IMP2380, BAG2 (Fab), and anti-kappa VHH domain
Fitted models: 9pv0

Deposition Authors: Suwatthee T , Gray JL, Ledger EVK, Wang D, Edwards A, Tate EW, Traaseth NJ

Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation
Gray JL, Ledger EVK, Suwatthee T , Lanyon-Hogg T, Burden TJ, Arvaniti K, Sefton A, Papagora LE, Clarke TB, Riley J, Pinto EG, Cunningham F, Gilbert IH, Gray D, Wang D, Read KD, Traaseth NJ , Edwards A, Tate EW
To Be Published