EMD-71880

Single-particle
2.52 Å
EMD-71880
3D View Gallery
Deposition: 31/07/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71880

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pv0 summary report (pdf.gz) Map-9pv0 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

NorA in outward-open conformation bound to inhibitor IMP2380

EMD-71880

Single-particle
2.52 Å
EMD-71880
3D View Gallery
Deposition: 31/07/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Staphylococcus aureus, Escherichia coli
Sample: NorA-BRIL in complex with IMP2380, BAG2 (Fab), and anti-kappa VHH domain
Fitted models: 9pv0

Deposition Authors: Suwatthee T, Gray JL, Ledger EVK, Wang D, Edwards A, Tate EW, Traaseth NJ

Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation
Gray JL, Ledger EVK, Suwatthee T, Lanyon-Hogg T, Burden TJ, Arvaniti K, Sefton A, Papagora LE, Clarke TB, Riley J, Pinto EG, Cunningham F, Gilbert IH, Gray D, Wang D, Read KD, Traaseth NJ, Edwards A, Tate EW
To Be Published