EMD-71783

Single-particle
3.29 Å
EMD-71783
3D View Gallery
Deposition: 22/07/2025
Map released: 20/08/2025
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71783
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9pqd summary report (pdf.gz) Map and 9pqd FULL report (pdf.gz)
EMICSS annotations (xml)

Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and compound Z7149

EMD-71783

Single-particle
3.29 Å
EMD-71783
3D View Gallery
Deposition: 22/07/2025
Map released: 20/08/2025
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and compound Z7149
Fitted models: 9pqd

Deposition Authors: Srinivasan K , Wu Y , Billesboelle C, Kim JY, Manglik A , Shoichet BK

Large library docking for polypharmacology
Wu Y , Vigneron S, Huang X, Braz J, Srinivasan K , Fink E, Xu X, Huebner H, Billesboelle C, Kim JY, Wang J, Pfeiffer T, Sakamoto K, Radchenko D, Moroz Y, Irwin J, Gmeiner P, Roth B, Basbaum A, Manglik A , Wetsel W, Shoichet BK
To Be Published