EMD-71772
Cryo-EM structure of K001-A1 Fab in complex with HIV-1 459C-OPT RnS DS-SOSIP Env trimer
EMD-71772
Single-particle3.01 Å
Deposition: 21/07/2025Map released: 17/12/2025
Last modified: 18/02/2026
Sample Organism:
Human immunodeficiency virus 1,
Macaca mulatta
Sample: HIV-1 Env 459C-OPT RnS DS-SOSIP in complex with antibody Fab
Fitted models: 9pnu
Deposition Authors: Wang S, Zhou T, Kwong PD, Morano NC, Shapiro L
Sample: HIV-1 Env 459C-OPT RnS DS-SOSIP in complex with antibody Fab
Fitted models: 9pnu
Deposition Authors: Wang S, Zhou T, Kwong PD, Morano NC, Shapiro L
Vaccine elicitation of HIV-1 neutralizing antibodies against both V2 apex and fusion peptide in rhesus macaques.
Duan H,
Nkolola JP,
Wang S,
Chaudhari J,
Teng IT,
Lavine C,
Parchment DK,
Sellers GS,
McKee K,
O'Dell S,
Choe M,
Du H,
Zhang B,
Perez AAE,
Rossler A,
Lasrado N,
Biju A,
Becker JE,
Carroll R,
Carson AS,
Henry AR,
Morano NC,
Mughal M,
Rawi R,
Roark RS,
Schramm CA,
Shen CH,
Smith SC,
Stephens T,
Tsybovsky Y,
Van Wazer DJ,
Wang H,
Yang Y,
Rutten L,
Langedijk JPM,
Cheng C,
Wang L,
Douek DC,
Koup RA,
Mascola JR,
Shapiro L,
Zhou T,
Doria-Rose NA,
Korber B,
Seaman MS,
Pierson TC,
Kwong PD,
Barouch DH
(2026) Cell Rep , 45 , 116905 - 116905
(2026) Cell Rep , 45 , 116905 - 116905
Grant Support: