EMD-71770

Single-particle
3.4 Å
EMD-71770
3D View Gallery
Deposition: 21/07/2025
Map released: 04/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71770

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pns summary report (pdf.gz) Map-9pns FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human serotonin transporter bound to small molecule zPZd in lipid nanodisc and NaCl

EMD-71770

Single-particle
3.4 Å
EMD-71770
3D View Gallery
Deposition: 21/07/2025
Map released: 04/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Human serotonin transporter in complex with Fab15B8 bound to zPZd in NaCl
Fitted models: 9pns

Deposition Authors: Billesboelle CB, Manglik A
Large Library Docking for Polypharmacology.
Wu Y, Vigneron S, Braz J, Srinivasan K , Fink EA , Huang XP, Xu X, Huebner H , Kim JY , Wang J , Pfeiffer T , Sakamoto K , Radchenko DS , Rodriguiz RM, Moroz YS , Irwin JJ, Gmeiner P , Billesboelle C, Roth BL , Basbaum AI, Manglik A, Wetsel WC, Shoichet BK
(2026) J Med Chem , 69 , 6210 - 6229
PUBMED: 41712624
DOI: doi:10.1021/acs.jmedchem.5c03810
ISSN: 0022-2623
ASTM: JMCMAR