EMD-71728

Single-particle
3.45 Å
EMD-71728
3D View Gallery
Deposition: 16/07/2025
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71728
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9pm6 summary report (pdf.gz) Map and 9pm6 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of modified Zika virus E protein dimer complexed with a neutralizing antibody OZ-D4 Fab

EMD-71728

Single-particle
3.45 Å
EMD-71728
3D View Gallery
Deposition: 16/07/2025
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Zika virus, Homo sapiens
Sample: Zika virus E protein dimer complex with a neutralizing antibody OZ-D4 Fab
Fitted models: 9pm6

Deposition Authors: Galkin A, Pozharski E , Li Y
Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk.
Wang Y , Galkin A, Shang X, Marin A, Jin S, Ye TJ , Bale S, Chiang CI , Chowdhury A, Chenine AL, Turonis A, Greenhouse J, Stone R, Wear J, Kar S, Andersen H , Huang YS , Vanlandingham DL, Higgs S, Lapidus RG, Fuerst T, Weber DJ , Wyatt RT, Iffland C, Pierson TC, Andrianov AK , Pozharski E , Li Y
(2025) Nat Commun , 16 , 11558 - 11558
PUBMED: 41429771
DOI: doi:10.1038/s41467-025-67447-4
ISSN: 2041-1723