EMD-71614
Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in post-translocation elongation state
EMD-71614
Single-particle3.54 Å
Deposition: 06/07/2025Map released: 06/05/2026
Last modified: 15/07/2026
Sample Organism:
Respiratory syncytial virus A2
Sample: Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in post-translocation elongation state
Fitted models: 9pfu
Deposition Authors: Cao D
,
Chen Z ,
Gao Y ,
Roesler C,
Gooneratne I ,
Liang B ,
Liang B
Sample: Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in post-translocation elongation state
Fitted models: 9pfu
Deposition Authors: Cao D
,
Chen Z ,
Gao Y ,
Roesler C,
Gooneratne I ,
Liang B ,
Liang B
Orchestrated and dynamic nucleotide addition cycle during respiratory syncytial virus early-stage elongation.
Cao D ,
Chen Z ,
Gao Y ,
Roesler C,
Gooneratne I ,
Mera C,
Zhuang L,
Slack J,
Nudell-Cook E,
Vy J,
Berry J,
Royal M,
Shaik M,
Youngs R,
Liang B
(2026) Nat Commun , 17
,
Chen Z ,
Gao Y ,
Roesler C,
Gooneratne I ,
Mera C,
Zhuang L,
Slack J,
Nudell-Cook E,
Vy J,
Berry J,
Royal M,
Shaik M,
Youngs R,
Liang B
(2026) Nat Commun , 17
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM130950 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24GM116788 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24GM116789 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24GM129539 (United States)
- Simons Foundation: SF349247 (United States)