EMD-71502

Single-particle
6.93 Å
EMD-71502
3D View Gallery
Deposition: 27/06/2025
Map released: 10/09/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71502

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of Synaptic Vesicle Protein 2A Bound to Levetiracetam and UCB1244283

EMD-71502

Single-particle
6.93 Å
EMD-71502
3D View Gallery
Deposition: 27/06/2025
Map released: 10/09/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: SV2A bound to levetiracetam and UCB1244283

Deposition Authors: Mittal A , Martin MF , Ledecq M , Horanyi PS , Coleman JA
Mechanisms underlying allosteric modulation of antiseizure medication binding to synaptic vesicle protein 2A (SV2A).
Mittal A , Martin MF , Provins L, Hall A , Ledecq M , Wolff C, Gillard M, Horanyi PS , Coleman JA
(2025) PNAS , 122 , e2510239122 - e2510239122
PUBMED: 40892927
DOI: doi:10.1073/pnas.2510239122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: