EMD-71501

Single-particle
3.42 Å
EMD-71501
3D View Gallery
Deposition: 27/06/2025
Map released: 10/09/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71501

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pcb summary report (pdf.gz) Map-9pcb FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of Synaptic Vesicle Protein 2A Bound to UCB-J

EMD-71501

Single-particle
3.42 Å
EMD-71501
3D View Gallery
Deposition: 27/06/2025
Map released: 10/09/2025
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: SV2A bound to UCB-J
Fitted models: 9pcb

Deposition Authors: Mittal A, Martin MF , Ledecq M, Horanyi PS , Coleman JA
Mechanisms underlying allosteric modulation of antiseizure medication binding to synaptic vesicle protein 2A (SV2A).
Mittal A, Martin MF , Provins L, Hall A , Ledecq M, Wolff C, Gillard M, Horanyi PS , Coleman JA
(2025) PNAS , 122 , e2510239122 - e2510239122
PUBMED: 40892927
DOI: doi:10.1073/pnas.2510239122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: