EMD-71423

Single-particle
3.27 Å
EMD-71423
3D View Gallery
Deposition: 24/06/2025
Map released: 19/11/2025
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71423

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9p9u summary report (pdf.gz) Map-9p9u FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

EGFR-KDD with compound2

EMD-71423

Single-particle
3.27 Å
EMD-71423
3D View Gallery
Deposition: 24/06/2025
Map released: 19/11/2025
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: EGFR-KDD and compound 2
Fitted models: 9p9u

Deposition Authors: Han L , Petrova ZO , Lemmon MA
The role of kinase domain dimerization in EGFR activation.
Petrova ZO , Han L , Tsutsui Y, Sheetz JB, Ashtekar KD, Lemmon MA
(2026) Structure , 34 , 426 - 440.e6
PUBMED: 41421344
DOI: doi:10.1016/j.str.2025.11.017
ISSN: 0969-2126
ASTM: STRUE6