EMD-71278

Single-particle
2.2 Å
EMD-71278
3D View Gallery
Deposition: 17/06/2025
Map released: 15/04/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71278

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9p4q summary report (pdf.gz) Map-9p4q FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of AAV.CAP-B10 complexed to AAVR-PKD2

EMD-71278

Single-particle
2.2 Å
EMD-71278
3D View Gallery
Deposition: 17/06/2025
Map released: 15/04/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: CAP-B10, Adeno-associated virus, Mus musculus
Sample: CAP-B10
Fitted models: 9p4q

Deposition Authors: Brittain TJ, Jang S
Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids.
Brittain TJ, Jang S , Coughlin GM, Hoang JD, Barcelona BH, Giriat I, Ristic F, Appling N, Chossis CPMA, Shay TF, Gradinaru V
(2026) Mol Ther , 34 , 3820 - 3837
PUBMED: 41906393
DOI: doi:10.1016/j.ymthe.2026.03.030
ISSN: 1525-0024