EMD-71252

Single-particle
3.5 Å
EMD-71252
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Deposition: 14/06/2025
Map released: 07/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71252
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9p3r summary report (pdf.gz) Map and 9p3r FULL report (pdf.gz)
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Zebrafish TRPM5 D797A mutant with 5mM calcium and 0.5mM CBTA

EMD-71252

Single-particle
3.5 Å
EMD-71252
3D View Gallery
Deposition: 14/06/2025
Map released: 07/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Danio rerio
Sample: zebrafish TRPM5 D797A mutant in GDN detergent with 5mM calcium anbd 0.5mM CBTA
Fitted models: 9p3r

Deposition Authors: Ruan Z, Du J, Lu W
A single allosteric site merges activation, modulation and inhibition in TRPM5.
Ruan Z, Lee J, Li Y, Orozco IJ, Du J, Lu W
(2026) Nat Chem Biol
PUBMED: 41491833
DOI: doi:10.1038/s41589-025-02097-7
ISSN: 1552-4469