EMD-71158

Single-particle
3.48 Å
EMD-71158
3D View Gallery
Deposition: 11/06/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71158

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9p24 summary report (pdf.gz) Map-9p24 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human cardiac sodium channel Nav1.5 in intermediate open state

EMD-71158

Single-particle
3.48 Å
EMD-71158
3D View Gallery
Deposition: 11/06/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mammalia, Homo sapiens
Sample: Sodium channel protein type 5 subunit alpha
Fitted models: 9p24

Deposition Authors: Biswas R, Chinthalapudi K
Structural and functional mechanisms underlying activation gate dynamics and IFM motif accessibility in human Na v 1.5.
Biswas R, Lopez-Serrano AL, Purohit A , Ramirez-Navarro A, Huang HL , Cheng X , Heissler SM , Deschenes I , Chinthalapudi K
(2026) Nat Commun , 17
PUBMED: 41698958
DOI: doi:10.1038/s41467-026-69672-x
ISSN: 2041-1723