EMD-70920
Heteromeric GluA1/A2-CNIH1 in the activated state, composite map of LBD-TMD
EMD-70920
Single-particle3.76 Å
Deposition: 31/05/2025Map released: 08/04/2026
Last modified: 08/04/2026
Sample Organism:
Rattus norvegicus,
Homo sapiens
Sample: Heteromeric GluA1/A2-CNIH1 + rr2b + glu (LBD-TMD, composite map)
Fitted models: 9ovv
Deposition Authors: Yen LY, Newton TP
,
Gangwar SP
,
Sobolevsky AI
Sample: Heteromeric GluA1/A2-CNIH1 + rr2b + glu (LBD-TMD, composite map)
Fitted models: 9ovv
Deposition Authors: Yen LY, Newton TP
,
Gangwar SP
,
Sobolevsky AI
Auxiliary subunits reshape structural asymmetry and functional plasticity in heterotetrameric GluA1/A2 AMPA receptor core.
Yen LY,
Newton TP
,
Yelshanskaya MV,
Aktolun M
,
Gangwar SP
,
Clausen RP,
Kurnikova MG
,
Sobolevsky AI
(2026) Nat Commun
,
Yelshanskaya MV,
Aktolun M
,
Gangwar SP
,
Clausen RP,
Kurnikova MG
,
Sobolevsky AI
(2026) Nat Commun
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24 GM129539 (United States)
- Simons Foundation: SF349247 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24 GM129541 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): F31NS132554 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS139087 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS083660 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS107253 (United States)
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): AR078814 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA206573 (United States)
