EMD-70862

Composite map
Single-particle
3.0 Å
EMD-70862
3D View Gallery
Deposition: 27/05/2025
Map released: 19/11/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70862
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9oty summary report (pdf.gz) Map and 9oty FULL report (pdf.gz)
EMICSS annotations (xml)

DDB1-CRBN with CK1 alpha, SB-405483, and DEG-47: composite map and model submission

EMD-70862

Composite map
Single-particle
3.0 Å
EMD-70862
3D View Gallery
Deposition: 27/05/2025
Map released: 19/11/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: DDB1(BPB deleted)-CRBN complex with Casein kinase 1 alpha, SB-405483, and DEG-47
Fitted models: 9oty

Deposition Authors: Rizvi Z, Lander GC
Identification of an allosteric site on the E3 ligase adapter cereblon.
Dippon VN, Rizvi Z, Choudhry AE, Chung CW, Alkuraya IF, Xu W, Tao XB, Jurewicz AJ, Schneck JL, Chen W, Curnutt NM, Kabir F, Chan KH, Queisser MA, Musetti C, Dai H, Lander GC, Benowitz AB, Woo CM
(2026) Nature
PUBMED: 41565821
DOI: doi:10.1038/s41586-025-09994-w
ISSN: 1476-4687
ASTM: NATUAS