EMD-70826

Composite map
Single-particle
3.54 Å
EMD-70826
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Deposition: 26/05/2025
Map released: 03/12/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70826
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ot6 summary report (pdf.gz) Map and 9ot6 FULL report (pdf.gz)
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Cryo-EM structure of the PI4KA complex bound to an EFR3 interfering nanobody (F3IN)

EMD-70826

Composite map
Single-particle
3.54 Å
EMD-70826
3D View Gallery
Deposition: 26/05/2025
Map released: 03/12/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Dimer of heterotetramers of PI4KA,TTC7B,FAM126A, and EFR3 interfering nanobody (F3IN)
Fitted models: 9ot6

Deposition Authors: Shaw AL, Suresh S, Yip CK , Burke JE
Development of an inhibitory TTC7B selective nanobody that blocks EFR3 recruitment of PI4KA.
Suresh S, Shaw AL, Akintola DK, Lunke M, Doerr S, Rohilla P, Balla T, Yip CK , Hansen SD, Cobb JA, Burke JE
(2025) J Biol Chem , 301 , 110886 - 110886
PUBMED: 41197736
DOI: doi:10.1016/j.jbc.2025.110886
ISSN: 1083-351X
ASTM: JBCHA3