EMD-70663
Cryo-EM structure of vaccine-elicited antibody T3_NB_G05 in complex with HIV Env trimer Q23-APEX-GT1.N187S
EMD-70663
Single-particle3.1 Å
Deposition: 15/05/2025Map released: 12/11/2025
Last modified: 25/02/2026
Sample Organism:
Mus musculus,
Homo sapiens,
Macaca mulatta
Sample: T3_NB_G05 Fab in complex with HIV Env trimer Q23-APEX-GT1.N187S
Fitted models: 9oog
Deposition Authors: Roark RS
,
Shapiro LS,
Kwong PD ,
Kwong PD
Sample: T3_NB_G05 Fab in complex with HIV Env trimer Q23-APEX-GT1.N187S
Fitted models: 9oog
Deposition Authors: Roark RS
,
Shapiro LS,
Kwong PD ,
Kwong PD
Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization.
Ghosh AR ,
Habib R ,
Mishra N ,
Roark RS ,
Akauliya M,
Albowaidey AA,
Allen JD ,
Amereh K,
Avillion G ,
Bottermann M ,
Liang B,
Chaudhary N ,
Callaghan S ,
Dye J ,
Li X ,
Ellis-Pugh JR ,
Roy Chowdhury R,
James NE ,
Liu X,
Maiorino L ,
Villavicencio PM ,
Nedellec R,
Oberoi P ,
Sowers KJ ,
Park Y ,
Prum T ,
Rodriguez L,
Ssozi M,
Torres JL ,
Walsh AA,
Warner JE ,
Weldon SR ,
Xu L ,
Wiehe K ,
Crispin M ,
Ward AB ,
Nair U ,
Hahn BH,
Burton DR ,
Shapiro L ,
Kwong PD ,
Irvine DJ ,
Andrabi R ,
Shaw GM ,
Batista FD
(2026) Sci Immunol , 11 , eadz5064 - eadz5064
,
Habib R ,
Mishra N ,
Roark RS ,
Akauliya M,
Albowaidey AA,
Allen JD ,
Amereh K,
Avillion G ,
Bottermann M ,
Liang B,
Chaudhary N ,
Callaghan S ,
Dye J ,
Li X ,
Ellis-Pugh JR ,
Roy Chowdhury R,
James NE ,
Liu X,
Maiorino L ,
Villavicencio PM ,
Nedellec R,
Oberoi P ,
Sowers KJ ,
Park Y ,
Prum T ,
Rodriguez L,
Ssozi M,
Torres JL ,
Walsh AA,
Warner JE ,
Weldon SR ,
Xu L ,
Wiehe K ,
Crispin M ,
Ward AB ,
Nair U ,
Hahn BH,
Burton DR ,
Shapiro L ,
Kwong PD ,
Irvine DJ ,
Andrabi R ,
Shaw GM ,
Batista FD
(2026) Sci Immunol , 11 , eadz5064 - eadz5064
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