Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-70612

Single-particle
9.72 Å
EMD-70612 Deposition: 13/05/2025
Map released: 04/06/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70612

Cryo-EM structure of neddylated PCMTD1-ELOBC-CUL5-RBX2 (N8-CRL5-PCMTD1)

EMD-70612

Single-particle
9.72 Å
EMD-70612 Deposition: 13/05/2025
Map released: 04/06/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Neddylated complex of PCMTD1, Elongins B and C, Cullin-5, and RING-box protein 2 (N8-CRL5-PCMTD1)
Fitted models: 9omf

Deposition Authors: Pang EZ, Zhao B, Flowers C, Oroudjeva E , Winters JB, Pandey V, Sawaya MR , Wohlschlegel W, Loo JA, Rodriguez JA, Clarke SG
Structural basis for L-isoaspartyl-containing protein recognition by the human PCMTD1 cullin-RING E3 ubiquitin ligase.
Pang EZ, Zhao B, Flowers C, Oroudjeva E , Winter JB, Pandey V, Sawaya MR , Wohlschlegel J, Loo JA, Rodriguez JA, Clarke SG
(2025) J Biol Chem , 301 , 110735 - 110735
PUBMED: 40975169
DOI: doi:10.1016/j.jbc.2025.110735
ISSN: 1083-351X
ASTM: JBCHA3