EMD-70443

Single-particle
3.9 Å
EMD-70443
3D View Gallery
Deposition: 30/04/2025
Map released: 11/06/2025
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70443

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ofu summary report (pdf.gz) Map-9ofu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map)

Dimer of HIF-1a-ARNT Heterodimers Complexed on 52-bp HRE/HAS

EMD-70443

Single-particle
3.9 Å
EMD-70443
3D View Gallery
Deposition: 30/04/2025
Map released: 11/06/2025
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dimer of two HIF-1a-ARNT heterodimers complexed on 52-bp HRE
Fitted models: 9ofu

Deposition Authors: Closson JD, Tiyani TT, Xu X , Gardner KH
Context-dependent variability of HIF heterodimers influences interactions with macromolecular and small molecule partners.
Closson JD, Xu X , Zhang M , Tiyani TT, Marcelino LP , Isiorho EA , Nagati JS , Garcia JA , Gardner KH
(2026) PNAS , 123 , e2514042123 - e2514042123
PUBMED: 42048441
DOI: doi:10.1073/pnas.2514042123
ISSN: 1091-6490
ASTM: PNASA6