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EMD-70345
BG505 MD39.3-CC5 SOSIP in complex with C3V5 epitope polyclonal Fabs isolated from HVTN302 human trial after dose 3 of mRNA-gp151-CD4KO immunization
EMD-70345
Single-particle28.0 Å
Deposition: 25/04/2025Map released: 27/08/2025
Last modified: 27/08/2025
Sample Organism:
Human immunodeficiency virus 1
Sample: BG505 MD39.3-CC5 SOSIP in complex with C3V5 epitope polyclonal Fabs isolated from HVTN302 human trial after dose 3 of mRNA-gp151-CD4KO immunization
Deposition Authors: Lee W-H
,
Ozorowski G ,
Ward AB
Sample: BG505 MD39.3-CC5 SOSIP in complex with C3V5 epitope polyclonal Fabs isolated from HVTN302 human trial after dose 3 of mRNA-gp151-CD4KO immunization
Deposition Authors: Lee W-H
,
Ozorowski G ,
Ward AB
Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial.
Parks KR ,
Moodie Z ,
Allen MA ,
Yen C,
Furch BD ,
MacPhee KJ ,
Ozorowski G ,
Heptinstall J ,
Hahn WO,
Zheng Z ,
Lu H,
Grant S,
Domin E ,
Duff MO ,
Seese A ,
Marini-Macouzet C,
Ballweber-Fleming L ,
Lee WH ,
Cottrell CA ,
Liguori A ,
Georgeson E ,
Alavi N ,
Kubitz M,
Phelps N ,
Seaton KE ,
Cohen KW ,
Anderson MA,
Mondal K ,
Laufer DS ,
Kublin JG ,
Ward AB ,
Hyrien O ,
De Rosa SC ,
Himansu S ,
Leav B,
Reuter C ,
Tomaras GD,
Montefiori D,
Walsh SR ,
Frank I ,
Sobieszczyk ME ,
Goepfert PA ,
Stephenson KE ,
Baden LR,
Van Tieu H ,
Keefer MC ,
Clark J ,
Riddler SA ,
Schief WR ,
McElrath MJ
(2025) Sci Transl Med , 17 , eady6831 - eady6831
,
Moodie Z ,
Allen MA ,
Yen C,
Furch BD ,
MacPhee KJ ,
Ozorowski G ,
Heptinstall J ,
Hahn WO,
Zheng Z ,
Lu H,
Grant S,
Domin E ,
Duff MO ,
Seese A ,
Marini-Macouzet C,
Ballweber-Fleming L ,
Lee WH ,
Cottrell CA ,
Liguori A ,
Georgeson E ,
Alavi N ,
Kubitz M,
Phelps N ,
Seaton KE ,
Cohen KW ,
Anderson MA,
Mondal K ,
Laufer DS ,
Kublin JG ,
Ward AB ,
Hyrien O ,
De Rosa SC ,
Himansu S ,
Leav B,
Reuter C ,
Tomaras GD,
Montefiori D,
Walsh SR ,
Frank I ,
Sobieszczyk ME ,
Goepfert PA ,
Stephenson KE ,
Baden LR,
Van Tieu H ,
Keefer MC ,
Clark J ,
Riddler SA ,
Schief WR ,
McElrath MJ
(2025) Sci Transl Med , 17 , eady6831 - eady6831
Grant Support: