EMD-70317

Single-particle
3.0 Å
EMD-70317
3D View Gallery
Deposition: 24/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70317
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ocj summary report (pdf.gz) Map and 9ocj FULL report (pdf.gz)
EMICSS annotations (xml)

Transporter associated with antigen processing (TAP) bound to the viral protein CPXV012 in the outward-facing open state

EMD-70317

Single-particle
3.0 Å
EMD-70317
3D View Gallery
Deposition: 24/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Cowpox virus
Sample: Ternary complex of the heterodimer TAP1 and TAP2 bound to the viral inhibitor CPXV012.
Fitted models: 9ocj

Deposition Authors: Lee J, Manon V , Chen J
Structurally diverse viral inhibitors converge on a shared mechanism to stall the antigen transporter TAP.
Lee J, Manon V , Chen J
(2025) PNAS , 122 , e2516676122 - e2516676122
PUBMED: 40956880
DOI: doi:10.1073/pnas.2516676122
ISSN: 1091-6490
ASTM: PNASA6