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EMD-70295

Helical reconstruction
2.5 Å
EMD-70295 Deposition: 23/04/2025
Map released: 25/06/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70295

Cryo-EM structure of alpha-synuclein filaments derived from the frontal cortex of the case of atypical multiple system atrophy

EMD-70295

Helical reconstruction
2.5 Å
EMD-70295 Deposition: 23/04/2025
Map released: 25/06/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Asymmetric homodimer filament of alpha-synuclein
Fitted models: 9obp

Deposition Authors: Enomoto M , Martinez-Valbuena I , Forrest SL, Xu X, Munhoz R, Li J, Rogaeva E , Lang AE, Kovacs GG
Lewy-MSA hybrid fold drives distinct neuronal alpha-synuclein pathology.
Enomoto M , Martinez-Valbuena I , Forrest SL, Xu X, Munhoz RP, Li J, Rogaeva E , Lang AE, Kovacs GG
(2025) Commun Biol , 8 , 929 - 929
PUBMED: 40523906
DOI: doi:10.1038/s42003-025-08355-7
ISSN: 2399-3642