Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-70295
Cryo-EM structure of alpha-synuclein filaments derived from the frontal cortex of the case of atypical multiple system atrophy
EMD-70295
Helical reconstruction2.5 Å
Deposition: 23/04/2025Map released: 25/06/2025
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: Asymmetric homodimer filament of alpha-synuclein
Fitted models: 9obp
Deposition Authors: Enomoto M
,
Martinez-Valbuena I
,
Forrest SL,
Xu X,
Munhoz R,
Li J,
Rogaeva E
,
Lang AE,
Kovacs GG
Sample: Asymmetric homodimer filament of alpha-synuclein
Fitted models: 9obp
Deposition Authors: Enomoto M
,
Martinez-Valbuena I
,
Forrest SL,
Xu X,
Munhoz R,
Li J,
Rogaeva E
,
Lang AE,
Kovacs GG
Lewy-MSA hybrid fold drives distinct neuronal alpha-synuclein pathology.
Enomoto M
,
Martinez-Valbuena I
,
Forrest SL,
Xu X,
Munhoz RP,
Li J,
Rogaeva E
,
Lang AE,
Kovacs GG
(2025) Commun Biol , 8 , 929 - 929
,
Martinez-Valbuena I
,
Forrest SL,
Xu X,
Munhoz RP,
Li J,
Rogaeva E
,
Lang AE,
Kovacs GG
(2025) Commun Biol , 8 , 929 - 929
Grant Support:
- National Institutes of Health/National Institute on Aging (NIH/NIA): (United States)
