EMD-70295

Helical reconstruction
2.5 Å
EMD-70295
3D View Gallery
Deposition: 23/04/2025
Map released: 25/06/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70295

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9obp summary report (pdf.gz) Map-9obp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of alpha-synuclein filaments derived from the frontal cortex of the case of atypical multiple system atrophy

EMD-70295

Helical reconstruction
2.5 Å
EMD-70295
3D View Gallery
Deposition: 23/04/2025
Map released: 25/06/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Asymmetric homodimer filament of alpha-synuclein
Fitted models: 9obp

Deposition Authors: Enomoto M , Martinez-Valbuena I , Forrest SL, Xu X, Munhoz R, Li J, Rogaeva E , Lang AE, Kovacs GG
Lewy-MSA hybrid fold drives distinct neuronal alpha-synuclein pathology.
Enomoto M , Martinez-Valbuena I , Forrest SL, Xu X, Munhoz RP, Li J, Rogaeva E , Lang AE, Kovacs GG
(2025) Commun Biol , 8 , 929 - 929
PUBMED: 40523906
DOI: doi:10.1038/s42003-025-08355-7
ISSN: 2399-3642