EMD-70276

Single-particle
3.44 Å
EMD-70276
3D View Gallery
Deposition: 20/04/2025
Map released: 04/02/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70276

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9oa9 summary report (pdf.gz) Map-9oa9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of anti-MHC-I mAb B1.23.2 Fc domains

EMD-70276

Single-particle
3.44 Å
EMD-70276
3D View Gallery
Deposition: 20/04/2025
Map released: 04/02/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of Anti-human-mAb B1.23.2 and MHC-I HLA-B44:05, Fc domains
Fitted models: 9oa9

Deposition Authors: Jiang J , Natarajan K , Margulies DH , Huang R, Margulies DH
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J , Panda AK, Natarajan K , Lei H , Sharma S, Boyd LF, Towler RR , Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N , Meier-Schellersheim M , Huang RK, Shevach EM , Margulies DH
(2026) Commun Biol , 9
PUBMED: 41629525
DOI: doi:10.1038/s42003-026-09641-8
ISSN: 2399-3642