EMD-70276

Single-particle
3.44 Å
EMD-70276
3D View Gallery
Deposition: 20/04/2025
Map released: 04/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70276
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9oa9 summary report (pdf.gz) Map and 9oa9 FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of anti-MHC-I mAb B1.23.2 Fc domains

EMD-70276

Single-particle
3.44 Å
EMD-70276
3D View Gallery
Deposition: 20/04/2025
Map released: 04/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of Anti-human-mAb B1.23.2 and MHC-I HLA-B44:05, Fc domains
Fitted models: 9oa9

Deposition Authors: Jiang J, Natarajan K, Margulies DH, Huang R, Margulies DH
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J, Panda AK, Natarajan K, Lei H, Sharma S, Boyd LF, Towler RR, Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N, Meier-Schellersheim M, Huang RK, Shevach EM, Margulies DH
(2026) Commun Biol
PUBMED: 41629525
DOI: doi:10.1038/s42003-026-09641-8
ISSN: 2399-3642