EMD-70246

Single-particle
2.44 Å
EMD-70246
3D View Gallery
Deposition: 17/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70246

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o9d summary report (pdf.gz) Map-9o9d FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Transporter associated with antigen processing (TAP) EQ mutant bound to the viral protein bUL49.5 in the outward-facing unkinked state

EMD-70246

Single-particle
2.44 Å
EMD-70246
3D View Gallery
Deposition: 17/04/2025
Map released: 10/09/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, bovine alphaherpesvirus 1
Sample: Ternary complex of the heterodimer TAP1 and TAP2 bound to the viral inhibitor UL49.5
Fitted models: 9o9d

Deposition Authors: Lee J, Manon V , Chen J
Structurally diverse viral inhibitors converge on a shared mechanism to stall the antigen transporter TAP.
Lee J, Manon V , Chen J
(2025) PNAS , 122 , e2516676122 - e2516676122
PUBMED: 40956880
DOI: doi:10.1073/pnas.2516676122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: