EMD-70225

Single-particle
3.91 Å
EMD-70225 Deposition: 15/04/2025
Map released: 17/12/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70225

Cryo-EM structure of primidone-bound rabbit TRPM3 having 2 resting and 2 activated subunits (para position) at 18 degrees Celsius

EMD-70225

Single-particle
3.91 Å
EMD-70225 Deposition: 15/04/2025
Map released: 17/12/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: rabbit TRPM3 in complex with the inhibitor primidone
Fitted models: 9o8f

Deposition Authors: Kumar S , Lu W , Du J
Structural basis for agonist and heat activation of nociceptor TRPM3.
Kumar S , Jin F, Park SJ , Choi W, Keuning SI, Massimino RP , Vu S, Lu W , Du J
(2026) Nat Struct Mol Biol , 33 , 34 - 42
PUBMED: 41136608
DOI: doi:10.1038/s41594-025-01692-5
ISSN: 1545-9985