EMD-70224

Helical reconstruction
3.1 Å
EMD-70224
3D View Gallery
Deposition: 15/04/2025
Map released: 18/03/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70224
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9o8e summary report (pdf.gz) Map and 9o8e FULL report (pdf.gz)
EMICSS annotations (xml)

amyloid fibril of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer's disease tau fibrils

EMD-70224

Helical reconstruction
3.1 Å
EMD-70224
3D View Gallery
Deposition: 15/04/2025
Map released: 18/03/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: amyloid fibril of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer's disease tau fibrils
Fitted models: 9o8e

Deposition Authors: Jiang YX , Sawaya MR , Abskharon R , Ge P , Boyer DR , Eisenberg DS
Structural evidence that RNA contributes to polymorphism of tau amyloid fibrils.
Abskharon R , Jiang YX , Sawaya MR , Ge P , Zhang J , Boyer DR , Dolinsky JL , Pi J, Cascio D , Guo F , Eisenberg DS
(2026) iScience , 29 , 115501 - 115501
PUBMED: 42006351
DOI: doi:10.1016/j.isci.2026.115501
ISSN: 2589-0042