EMD-70223

Single-particle
3.41 Å
EMD-70223
3D View Gallery
Deposition: 15/04/2025
Map released: 25/02/2026
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70223

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o8d summary report (pdf.gz) Map-9o8d FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of primidone-bound rabbit TRPM3 having 2 resting and 2 activated subunits (ortho position) at 18 degrees Celsius

EMD-70223

Single-particle
3.41 Å
EMD-70223
3D View Gallery
Deposition: 15/04/2025
Map released: 25/02/2026
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: rabbit TRPM3 in complex with the inhibitor primidone
Fitted models: 9o8d

Deposition Authors: Kumar S , Lu W , Du J
Structural basis for agonist and heat activation of nociceptor TRPM3.
Kumar S , Jin F , Park SJ , Choi W , Keuning SI , Massimino RP , Vu S, Lu W , Du J
(2026) Nat Struct Mol Biol , 33 , 34 - 42
PUBMED: 41136608
DOI: doi:10.1038/s41594-025-01692-5
ISSN: 1545-9985