EMD-70143

Single-particle
3.19 Å
EMD-70143
3D View Gallery
Deposition: 10/04/2025
Map released: 17/12/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70143

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9o5k summary report (pdf.gz) Map-9o5k FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human SWELL1-PSA heterocomplex

EMD-70143

Single-particle
3.19 Å
EMD-70143
3D View Gallery
Deposition: 10/04/2025
Map released: 17/12/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heterocomplex of SWELL1 and PSA
Fitted models: 9o5k

Deposition Authors: Hagino T, Twomey EC, Qiu Z
Puromycin-sensitive aminopeptidase acts as an inhibitory auxiliary subunit of volume-regulated anion channels and regulates cGAMP transport.
Zheng W, Hagino T, Wang H, Cheng HY, Koylass N, Chen KH, Wang H, Mani S, Mondal AK, Twomey EC, Qiu Z
(2025) Mol Cell , 85 , 4621 - 4632.e7
PUBMED: 41371222
DOI: doi:10.1016/j.molcel.2025.11.014
ISSN: 1097-2765
ASTM: MOCEFL