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EMD-70093

Helical reconstruction
2.59 Å
EMD-70093
3D View Gallery
Deposition: 08/04/2025
Map released: 23/04/2025
Last modified: 23/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70093
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9o4b summary report (pdf.gz) Map and 9o4b FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of in-vitro alpha-synuclein fibril bound with Exemplar-6 PET-radioligand

EMD-70093

Helical reconstruction
2.59 Å
EMD-70093
3D View Gallery
Deposition: 08/04/2025
Map released: 23/04/2025
Last modified: 23/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: alpha-synuclein fibril with Exemplar-6 PET-radioligand
Fitted models: 9o4b

Deposition Authors: Sanchez JC , Perez RM, Borcik CG , Guarino DS, Dhavala DD, Baumgardt JK, Shaffer KD, Kotzbauer PT, Mach RH, Rienstra CM , Petersson EJ , Wright ER

Complementary Structural and Chemical Biology Methods Reveal the Basis for Selective Radioligand Binding to Alpha-Synuclein in MSA Tissue
Sanchez JC , Perez RM, Borcik CG , Guarino DS, Dhavala DD, Baumgardt JK, Shaffer KD, Kotzbauer PT, Mach RH, Rienstra CM , Petersson EJ , Wright ER
To Be Published