EMD-69323

Single-particle
3.5 Å
EMD-69323
3D View Gallery
Deposition: 23/02/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-69323

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-23wo summary report (pdf.gz) Map-23wo FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the de novo designed metalloprotease DP221 E85Q mutant

EMD-69323

Single-particle
3.5 Å
EMD-69323
3D View Gallery
Deposition: 23/02/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Homo sapiens
Sample: de novo designed metalloprotease DP221 E85Q mutant
Fitted models: 23wo

Deposition Authors: Qu YN, Cao LX
De novo design of metalloproteases for targeted amyloid-beta cleavage
Qu Y, Wang C, Zhu H, Wang Y, Cao L
(2026) Vita
DOI: doi:10.15302/vita.2026.07.0055
ISSN: 2097-7468