EMD-68739

Single-particle
3.21 Å
EMD-68739
3D View Gallery
Deposition: 26/01/2026
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-68739

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-22wt summary report (pdf.gz) Map-22wt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

local refinement of 5HT2BR-fab heterotrimer in complex with a novel antagonist IHCH-2330

EMD-68739

Single-particle
3.21 Å
EMD-68739
3D View Gallery
Deposition: 26/01/2026
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: local refinemnent of 5-HT2B receptor bound to IHCH-2330 in complex with a fab (P2C2) obtained by cryo-electron microscopy (cryoEM)
Fitted models: 22wt

Deposition Authors: Tang L, Ji X, Cheng J, Wang S

Mechanistic Basis for 5-HT2AR Over 5-HT2BR Activation
Tang L, Ji X, Wang Y, Cao D, Li H, He L, Cheng J, Wang S
To Be Published