EMD-68737

Single-particle
3.2 Å
EMD-68737
3D View Gallery
Deposition: 26/01/2026
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-68737

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-22wr summary report (pdf.gz) Map-22wr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

local refinement of 5HT2AR-miniGq heterotrimer in complex with a selective agonist IHCH-2330

EMD-68737

Single-particle
3.2 Å
EMD-68737
3D View Gallery
Deposition: 26/01/2026
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: local refinement of 5-HT2A receptor bound to IHCH-2330 in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Fitted models: 22wr

Deposition Authors: Tang L, Ji X, Cheng J, Wang S

Mechanistic Basis for 5-HT2AR Over 5-HT2BR Activation
Tang L, Ji X, Wang Y, Cao D, Li H, He L, Cheng J, Wang S
To Be Published